Natural Biostimulatory Treatments to Rejuvenate Your Skin

In 2025, we’ve uncovered quite a few ways to use natural substances to drive positive outcomes. Take biostimulation, for example. Originally used to help remediate environmental damage, this technique involves using nutrients to encourage desired changes. 

Biostimulation has expanded, and Elaine Phuah, DO, MBA, FACOI, applies this same principle to help people here at Hanami Medspa in Fort Worth, Texas. Dr. Phuah and our team offer several ways to tap into your skin’s natural regenerative abilities with biostimulatory treatments. With options like platelet-rich fibrin (PRF) filler, radiofrequency (RF) microneedling, AQUAGOLD® fine touchTM microchanneling, and specialized dermal fillers, we can provide biostimulation to support healthy, great-looking skin. 

Let’s look more closely at these four treatments. 

#1: PRF bio-filler

This biostimulatory option gives you an alternative to dermal fillers. Instead of synthetic ingredients, it uses platelet-rich fibrin. Dr. Phuah gets this PRF from a small sample of your own blood.

When injected into areas where you want more volume, the PRF bio-filler delivers resources your skin can use to generate new collagen to plump the area. The filler contains growth factors, for example, which stimulate tissue rejuvenation. The PRF also introduces a fibrin matrix that can serve as a scaffolding to support your skin. 

In short, PRF filler uses a natural ingredient — your own blood — instead of a synthetic dermal filler. 

#2: RF microneedling

During microneedling, Dr. Phuah uses a specialized device to create tiny pinpricks in your skin. At the same time, the device delivers radiofrequency. 

Your body registers the treatment as an injury and goes to work to “heal” the treated area. Together, the RF and microneedling stimulate your body’s natural ability to generate new, healthy skin cells. 

In this way, RF microneedling can move you toward your cosmetic goals by supporting the following:

• The minimization of the visibility of scars
• A more even skin tone 
• Skin tightening
• Wrinkle reduction

The microneedling device uses needles as fine as a strand of hair. That minimizes your discomfort and shortens your recovery time after treatment. In fact, you usually only need to worry about some redness for a day or so. 

#3: AQUAGOLD fine touch microchanneling

This treatment gives Dr. Phuah a sophisticated way to deliver PRF into your skin. It works similarly to microneedling but uses 24K gold sterile needles and a gentler approach. That means an even shorter downtime than microneedling. 

With both microneedling and microchanneling, you should see some improvement in your skin with just one treatment. But repeat sessions — usually, about three appointments, each spaced about a month apart — can deliver even more biostimulation. This, in turn, yields more dramatic improvement in your skin.

#4: Sculptra® and Radiesse®

Dr. Phuah offers dermal fillers that introduce biostimulatory elements to trigger rejuvenation in your skin. With Sculptra®, for example, she can inject poly-L-lactic acid (PLLA), a biocompatible way to encourage collagen production in your skin. 

She can also use Radiesse®, which works similarly but uses calcium hydroxyapatite (CaHA) microspheres to stimulate collagen production. 

These biostimulatory fillers give you a way to replenish volume by encouraging your body’s natural collagen-creating abilities. That gives you a way to turn back the clock. 

In short, Dr. Phuah has several ways to apply the principle of biostimulation to help you move toward your cosmetic goals. Schedule a consultation with our team to explore your options and see which might be best for your unique skin. Call us at Hanami Medspa or make an appointment online today.